BDBM50170131 1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione::1-benzyl-7-phenyl-3-propyl-1H-pyrrolo[1,2-a]purine-2,4(3H,6H)-dione::CHEMBL193100

SMILES CCCn1c(=O)n(Cc2ccccc2)c2nc3C=C(Cn3c2c1=O)c1ccccc1

InChI Key InChIKey=ULFOXVWHSODZOV-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50170131   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170131(1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]pur...)
Affinity DataKi:  200nMAssay Description:Inhibition of [3H]MRE3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; range is 134 to 297 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170131(1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]pur...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]MRE3008F20 from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170131(1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]pur...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170131(1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]pur...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-ZM 241385 binding to human adenosine A2a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170131(1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]pur...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human cloned adenosine A2B cells expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170131(1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]pur...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50170131(1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]pur...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed