BDBM50170252 CHEMBL425180::N-{5-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-pyridin-2-yl}-methanesulfonamide

SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)nc2)cc1

InChI Key InChIKey=OOQOQWMJQKVIAT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170252   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170252(N-{5-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-py...)
Affinity DataKi:  177nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170252(N-{5-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-py...)
Affinity DataKi:  4.10E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed