BDBM50170391 3-Phenyl-propynoic acid [4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-amide::CHEMBL360996

SMILES CN(C)C1CCN(C1)c1ccc(NC(=O)C#Cc2ccccc2)cc1

InChI Key InChIKey=RGPASQKSEJIRKR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170391   

TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50170391(3-Phenyl-propynoic acid [4-(3-dimethylamino-pyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50170391(3-Phenyl-propynoic acid [4-(3-dimethylamino-pyrrol...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human MCH-R1 evaluated by its ability to displace radioligand [125I]Tyr13]-MCHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed