BDBM50170438 6-(4-Chloro-phenylsulfanyl)-4-((R)-3-{[(4R,5S)-4-(4-fluoro-phenyl)-piperidin-3-ylmethyl]-amino}-butyl)-2-(4-methoxy-phenyl)-2H-pyridazin-3-one::CHEMBL362129

SMILES COc1ccc(cc1)-n1nc(Sc2ccc(Cl)cc2)cc(CC[C@@H](C)NC[C@H]2CNCC[C@@H]2c2ccc(F)cc2)c1=O

InChI Key InChIKey=PWXFIVWHBYGMBN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170438   

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170438(6-(4-Chloro-phenylsulfanyl)-4-((R)-3-{[(4R,5S)-4-(...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [125I]-NDP- alpha-MSH binding to human melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170438(6-(4-Chloro-phenylsulfanyl)-4-((R)-3-{[(4R,5S)-4-(...)
Affinity DataEC50:  470nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed