BDBM50171130 CHEMBL372509::Naphthalene-2-carboxylic acid [(S)-1-[((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-methyl]-5-(2-methoxy-benzoyl)-2-oxo-[1,5]diazocan-3-yl]-amide

SMILES COc1ccccc1C(=O)N1CCCN(CC(=O)N[C@H]2CC(=O)OC2O)C(=O)[C@H](C1)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=BTHOKXQBJVTFEI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171130   

TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171130(Naphthalene-2-carboxylic acid [(S)-1-[((S)-2-hydro...)
Affinity DataIC50: 38nMAssay Description:Inhibition of caspase-1 using fluorogenic substrate and BMG Fluostar plate reader for 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171130(Naphthalene-2-carboxylic acid [(S)-1-[((S)-2-hydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of caspase 8 using fluorogenic substrate and BMG Fluostar plate reader for 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171130(Naphthalene-2-carboxylic acid [(S)-1-[((S)-2-hydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of caspase 3 using fluorogenic substrate and BMG Fluostar plate reader for 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed