BDBM50171250 CHEMBL197640::[3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-[5-(1-methyl-piperidin-4-yloxy)-quinazolin-4-yl]-amine

SMILES CN1CCC(CC1)Oc1cccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12

InChI Key InChIKey=VQXONFAAUSCWAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171250   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171250(CHEMBL197640 | [3-Chloro-4-(3-fluoro-benzyloxy)-ph...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against EGFR kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171250(CHEMBL197640 | [3-Chloro-4-(3-fluoro-benzyloxy)-ph...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against erbB2 autophosphorylation in MCF-7 breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed