BDBM50171257 CHEMBL193578::[3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-[5-(tetrahydro-pyran-4-yloxy)-quinazolin-4-yl]-amine

SMILES Clc1cc(Nc2ncnc3cccc(OC4CCOCC4)c23)ccc1OCc1ccccn1

InChI Key InChIKey=NGKDXIDMJWVNHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171257   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171257(CHEMBL193578 | [3-Chloro-4-(pyridin-2-ylmethoxy)-p...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory concentration against EGFR kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171257(CHEMBL193578 | [3-Chloro-4-(pyridin-2-ylmethoxy)-p...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration against erbB2 kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed