BDBM50171260 3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-ol::CHEMBL371899

SMILES CN1CCN(CCc2c[nH]c3cccc(O)c23)CC1

InChI Key InChIKey=OOWKQSMXJCKWOK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50171260   

Target5-hydroxytryptamine receptor 2C(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171260(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Affinity DataKi:  103nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]mesulergine as radioligand with the compound (10 uM) disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171260(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Affinity DataKi:  116nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]LSD as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50171260(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]ketanserin as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171260(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Affinity DataKi:  9.75E+3nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]ketanserin as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50171260(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]mesulergine as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed