BDBM50171262 1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol::CHEMBL198124

SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12

InChI Key InChIKey=HVOYRIYIBILDHN-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50171262   

Target5-hydroxytryptamine receptor 2C(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataKi:  4.40nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]mesulergine as radioligand with the compound (10 uM) disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataKi:  5.80nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]LSD as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataKi:  14nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]mesulergine as radioligand with the compound (10 uM) disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataKi:  15.7nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]mesulergine as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataEC50:  32nMAssay Description:Effective concentration required for accumulation of [3H]inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataKi:  200nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]ketanserin as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataKi:  310nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]ketanserin as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171262(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Affinity DataEC50:  595nMAssay Description:Effective concentration required for accumulation of [3H]inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed