BDBM50171267 3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indol-4-ol::CHEMBL445331

SMILES Oc1cccc2[nH]cc(CCN3CCCc4ccccc34)c12

InChI Key InChIKey=QLWAKNNMOFDNHB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50171267   

Target5-hydroxytryptamine receptor 2C(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171267(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Affinity DataKi:  468nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]mesulergine as radioligand with the compound (10 uM) disso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50171267(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]mesulergine as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50171267(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Affinity DataKi:  5.57E+3nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]LSD as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50171267(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Affinity DataKi:  8.37E+3nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]ketanserin as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed