BDBM50171275 (+)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-1-methyl-6-(trifluoromethyl)quinolin-2(1H)-one::(-)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-1-methyl-6-(trifluoromethyl)quinolin-2(1H)-one::4-(5-Chloro-2-hydroxy-phenyl)-3-(2-hydroxy-ethyl)-1-methyl-6-trifluoromethyl-1H-quinolin-2-one::4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-1-methyl-6-(trifluoromethyl)quinolin-2(1H)-one::CHEMBL381679

SMILES Cn1c2ccc(cc2c(-c2cc(Cl)ccc2O)c(CCO)c1=O)C(F)(F)F

InChI Key InChIKey=MBTCZBZTIMYUQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171275   

TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171275(4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-1-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed