BDBM50171536 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfonyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL194237

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)S(C)(=O)=O

InChI Key InChIKey=VRUQYJXYEALKCT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171536   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  96nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  96nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171536(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfo...)
Affinity DataIC50:  51nMAssay Description:Inhibitory activity against matrix metallopeptidase 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed