BDBM50171538 4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-carboxylic acid hydroxyamide::CHEMBL196092

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCOCC1C(=O)NO

InChI Key InChIKey=SEOIKBYFTLCBTF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171538   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  162nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  162nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171538(4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-c...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against matrix metallopeptidase 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed