BDBM50171629 5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-1H-indole-2-carboxylic acid [3-(4-methylsulfamoyl-phenylcarbamoyl)-phenyl]-amide::CHEMBL197247

SMILES CNS(=O)(=O)c1ccc(NC(=O)c2cccc(NC(=O)c3cc4cc(NC(=O)CC(C)(C)C)ccc4n3Cc3ccccc3F)c2)cc1

InChI Key InChIKey=REDMUQMEGPUGBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171629   

TargetEndothelin-converting enzyme 1(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171629(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed