BDBM50171760 3-(2-Chloro-benzyl)-7-methyl-[1,8]naphthyridin-4-ol::CHEMBL195357

SMILES Cc1ccc2c(O)c(Cc3ccccc3Cl)cnc2n1

InChI Key InChIKey=TVGXHFOPOIUKGO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50171760   

TargetAdenosine receptor A2a(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171760(3-(2-Chloro-benzyl)-7-methyl-[1,8]naphthyridin-4-o...)
Affinity DataKi:  980nMAssay Description:Inhibition of [3H]CGS-21680 binding to adenosine A2a receptor of human striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171760(3-(2-Chloro-benzyl)-7-methyl-[1,8]naphthyridin-4-o...)
Affinity DataKi:  4.16E+3nMAssay Description:Inhibition of [3H]CHA binding to adenosine A1 receptor of human brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171760(3-(2-Chloro-benzyl)-7-methyl-[1,8]naphthyridin-4-o...)
Affinity DataKi:  8.73E+3nMAssay Description:Inhibition of [3H]CHA binding to adenosine A1 receptor of bovine brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171760(3-(2-Chloro-benzyl)-7-methyl-[1,8]naphthyridin-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]CGS-21680 binding to adenosine A2a receptor of bovine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed