BDBM50171771 7-Amino-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 4-chloro-benzylamide::CHEMBL196306

SMILES Nc1ccc2c(O)c(cnc2n1)C(=O)NCc1ccc(Cl)cc1

InChI Key InChIKey=TVYCDYDWZLPFMY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50171771   

TargetAdenosine receptor A2a(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171771(7-Amino-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-car...)
Affinity DataKi:  500nMAssay Description:Inhibition of [3H]CGS-21680 binding to adenosine A2a receptor of human striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171771(7-Amino-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-car...)
Affinity DataKi:  540nMAssay Description:Inhibition of [3H]CGS-21680 binding to adenosine A2a receptor of bovine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171771(7-Amino-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-car...)
Affinity DataKi:  4.49E+3nMAssay Description:Inhibition of [3H]CHA binding to adenosine A1 receptor of bovine brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171771(7-Amino-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-car...)
Affinity DataKi:  6.24E+3nMAssay Description:Inhibition of [3H]CHA binding to adenosine A1 receptor of human brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed