BDBM50171783 7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 4-chloro-benzylamide::CHEMBL195522

SMILES Cc1ccc2c(O)c(cnc2n1)C(=O)NCc1ccc(Cl)cc1

InChI Key InChIKey=BCPIVBRTJNYLEK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50171783   

TargetAdenosine receptor A2a(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171783(7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-ca...)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H]CGS-21680 binding to adenosine A2a receptor of human striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171783(7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-ca...)
Affinity DataKi:  210nMAssay Description:Inhibition of [3H]CGS-21680 binding to adenosine A2a receptor of bovine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171783(7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-ca...)
Affinity DataKi:  1.63E+3nMAssay Description:Inhibition of [3H]CHA binding to adenosine A1 receptor of human brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50171783(7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-ca...)
Affinity DataKi:  1.74E+3nMAssay Description:Inhibition of [3H]CHA binding to adenosine A1 receptor of bovine brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed