BDBM50171839 4-{3-[1-(4-Bromo-phenyl)-ethyl]-8-tert-butyl-2-oxo-1,3-diaza-spiro[4.5]dec-1-ylmethyl}-N-(2H-tetrazol-5-yl)-benzamide::CHEMBL196844

SMILES CC(c1ccc(Br)cc1)N1CC2(CCC(C(C)(C)C)CC2)N(Cc2ccc(C(=O)Nc3nnn[nH]3)cc2)C1=O

InChI Key InChIKey=UURKGMHNYJQPCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171839   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50171839BDBM50171839(4-{3-[1-(4-Bromo-phenyl)-ethyl]-8-tert-butyl-2-oxo...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50171839BDBM50171839(4-{3-[1-(4-Bromo-phenyl)-ethyl]-8-tert-butyl-2-oxo...)
Affinity DataIC50: 164nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed