BDBM50172027 2-Cyclohexylmethyl-4-(5-fluoro-2-hydroxy-phenyl)-2-hydroxy-4-methyl-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide::CHEMBL194802

SMILES CC(C)(CC(O)(CC1CCCCC1)C(=O)Nc1ccc2C(=O)OCc2c1)c1cc(F)ccc1O

InChI Key InChIKey=ZZWNDPPQMABJJG-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172027   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172027(2-Cyclohexylmethyl-4-(5-fluoro-2-hydroxy-phenyl)-2...)
Affinity DataIC50: 20nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172027(2-Cyclohexylmethyl-4-(5-fluoro-2-hydroxy-phenyl)-2...)
Affinity DataIC50: 42nMAssay Description:Binding affinity towards progesterone receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172027(2-Cyclohexylmethyl-4-(5-fluoro-2-hydroxy-phenyl)-2...)
Affinity DataEC50:  130nMAssay Description:Effective concentration against inhibition of Dexamethasone induced glucocorticoid receptor transactivation of mouse mammary tumor virus luciferase g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172027(2-Cyclohexylmethyl-4-(5-fluoro-2-hydroxy-phenyl)-2...)
Affinity DataIC50: 140nMAssay Description:Binding affinity towards mineralocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed