BDBM50172106 CHEMBL3809897
SMILES CC(C)(C)CCNC(=O)CCc1cc2cc(ccc2nc1N)-c1ccccc1C#Cc1ccc(NC(=O)c2ccc(F)cc2)cn1
InChI Key InChIKey=LXBIVXKQYPZTSX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50172106
Affinity DataIC50: 58nMAssay Description:Inhibition of Cathepsin D (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant BACE1 expressed in HEK293 cells using peptide sequence EVNLAAEF as substrate preincubated for 60 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 458nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair