BDBM50172759 3-(3-Methylamino-propyl)-1-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one::CHEMBL372318

SMILES CNCCCC1Cc2ccccc2N(C1=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=GTKJFGPZQFGMLW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50172759   

TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50172759(3-(3-Methylamino-propyl)-1-(4-trifluoromethyl-phen...)
Affinity DataKi: >100nMAssay Description:Inhibition of monoamine reuptake at serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50172759(3-(3-Methylamino-propyl)-1-(4-trifluoromethyl-phen...)
Affinity DataKi: >200nMAssay Description:Inhibition of monoamine reuptake at dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50172759(3-(3-Methylamino-propyl)-1-(4-trifluoromethyl-phen...)
Affinity DataKi:  1.43E+3nMAssay Description:Inhibition of monoamine reuptake at norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed