BDBM50173458 6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-ylamino)-chromen-2-one::CHEMBL197797

SMILES Clc1ccc2oc(=O)cc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1

InChI Key InChIKey=OPTNEFBOFIJLSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173458   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173458(6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-yl...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]MCHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173458(6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-yl...)
Affinity DataIC50: 92nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed