BDBM50173681 CHEMBL197883::[5-(3-Bromo-phenyl)-pyridazin-3-yl]-ethyl-amine

SMILES CCNc1cc(cnn1)-c1cccc(Br)c1

InChI Key InChIKey=UOYBEURVYWDNBS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173681   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173681(CHEMBL197883 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  3.5nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173681(CHEMBL197883 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  3.80nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173681(CHEMBL197883 | [5-(3-Bromo-phenyl)-pyridazin-3-yl]...)
Affinity DataKi:  7.30nMpH: 7.4Assay Description:Displacement of [3H]-Ro- 15-1788 binding from human recombinant Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in mouse fibroblast ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed