BDBM50173820 (Z)-6-(3-Fluoro-5-trifluoromethyl-phenyl)-6-(3-methoxy-7-methyl-benzo[d]isoxazol-5-yl)-hex-5-enoic acid methyl ester::(Z)-methyl 6-(3-fluoro-5-(trifluoromethyl)phenyl)-6-(3-methoxy-7-methylbenzo[d]isoxazol-5-yl)hex-5-enoate::CHEMBL372175

SMILES COC(=O)CCC\C=C(/c1cc(F)cc(c1)C(F)(F)F)c1cc(C)c2onc(OC)c2c1

InChI Key InChIKey=UOYWGQHDLBBPMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173820   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50173820((Z)-methyl 6-(3-fluoro-5-(trifluoromethyl)phenyl)-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase assessed as incorporation of [32P]GTP into poly(rC).oligo(dG) (rCdG) homopolymer template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50173820((Z)-methyl 6-(3-fluoro-5-(trifluoromethyl)phenyl)-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed