BDBM50173843 4-(3,5-dichlorophenylamino)-6-(2-morpholinoethylamino)-1,7-naphthyridine-3-carbonitrile::CHEMBL198905

SMILES Clc1cc(Cl)cc(Nc2c(cnc3cnc(NCCN4CCOCC4)cc23)C#N)c1

InChI Key InChIKey=QXGZFXTTXWORPP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173843   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173843(4-(3,5-dichlorophenylamino)-6-(2-morpholinoethylam...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed