BDBM50173847 (S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylpropylamino)-1,7-naphthyridine-3-carbonitrile::CHEMBL196771

SMILES CC[C@H](Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N)c1ccccc1

InChI Key InChIKey=JJWPJEKOLAXHRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173847   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173847((S)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylpr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed