BDBM50174001 CHEMBL381019::N-[(S)-1-(4-Methyl-benzyl)-pyrrolidin-3-yl]-3-thiophen-2-yl-benzamide

SMILES Cc1ccc(CN2CC[C@@H](C2)NC(=O)c2cccc(c2)-c2cccs2)cc1

InChI Key InChIKey=UPEHPUZOPHDONV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174001   

TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50174001(N-[(S)-1-(4-Methyl-benzyl)-pyrrolidin-3-yl]-3-thio...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D4.2 receptor in HEK298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50174001(N-[(S)-1-(4-Methyl-benzyl)-pyrrolidin-3-yl]-3-thio...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]spiperone from human dopamine D2(short) receptor in rat pituitary GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50174001(N-[(S)-1-(4-Methyl-benzyl)-pyrrolidin-3-yl]-3-thio...)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]ketanserin from cloned human 5HT2A receptor in HEK298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed