BDBM50174210 3-Cyclopropylmethoxy-5-(5-pyridin-2-yl-tetrazol-2-yl)-benzonitrile::CHEMBL372782

SMILES N#Cc1cc(OCC2CC2)cc(c1)-n1nnc(n1)-c1ccccn1

InChI Key InChIKey=XYEMKDFMIAIYDL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174210   

TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50174210(3-Cyclopropylmethoxy-5-(5-pyridin-2-yl-tetrazol-2-...)
Affinity DataKi:  271nMAssay Description:Ability to displace [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine from binding to metabotropic glutamate receptor 5 in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50174210(3-Cyclopropylmethoxy-5-(5-pyridin-2-yl-tetrazol-2-...)
Affinity DataIC50: 975nMAssay Description:In vitro functional activity measured by changes in cytosolic [Ca2+] concentrations against rat metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed