BDBM50174266 CHEMBL198525::N-(2-(4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)ethyl)-5-(2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide::N-(2-(4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)ethyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

SMILES O=C(CCCCC1SCC2NC(=O)NC12)NCCN1CCC(=CC1)c1c[nH]c2ccccc12

InChI Key InChIKey=MVDIHPTYPOOXGQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174266   

TargetSodium-dependent serotonin transporter(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50174266(N-(2-(4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-y...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50174266(N-(2-(4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-y...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]serotonin from human SERT expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50174266(N-(2-(4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-y...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity of compound bound to streptavidin-conjugated quantum dots against human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed