BDBM50174931 CHEMBL198752::N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazolin-4-amine

SMILES COc1ccc(Cl)c(Nc2ncnc3cc(OCCCN4CCN(C)CC4)cc(OC(C)C)c23)n1

InChI Key InChIKey=MPNHPBKFHQKFKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174931   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174931(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174931(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 680nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed