BDBM50174941 CHEMBL197186::N-(5-chloro-2-methoxypyridin-4-yl)-7-(3-morpholinopropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine

SMILES COc1cc(Nc2ncnc3cc(OCCCN4CCOCC4)cc(OC4CCOCC4)c23)c(Cl)cn1

InChI Key InChIKey=RGGXAEJCXZWVDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174941   

TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174941(N-(5-chloro-2-methoxypyridin-4-yl)-7-(3-morpholino...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174941(N-(5-chloro-2-methoxypyridin-4-yl)-7-(3-morpholino...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed