BDBM50175041 CHEMBL3809034

SMILES CNC(=O)CCCCC[C@H](NC(=O)c1cncs1)c1ncc([nH]1)-c1ccc2ccccc2c1

InChI Key InChIKey=LKKXTQKFAXKMAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175041   

TargetHistone deacetylase 3(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50175041(CHEMBL3809034)
Affinity DataIC50: 235nMAssay Description:Inhibition of human recombinant his tagged HDAC3 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50175041(CHEMBL3809034)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human His-tagged HDAC1 expressed in insect cells preincubated for 10 mins followed by addition of FLUOR DE LYS as fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50175041(CHEMBL3809034)
Affinity DataIC50: 325nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed