BDBM50175503 CHEMBL197696::Dimethyl-carbamic acid (R)-2-methyl-1-[2-(4-nitro-phenoxy)-ethyl]-2,3-dihydro-1H-benzo[c]azepin-7-yl ester
SMILES CN(C)C(=O)Oc1ccc2[C@@H](CCOc3ccc(cc3)[N+]([O-])=O)N(C)CC=Cc2c1
InChI Key InChIKey=XUOUWGWIRPBWCW-OAQYLSRUSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50175503
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse brain acetylcholinesterase by Ellman's methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of rat synaptosome SERT assessed as reduction in [3H]5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of rat synaptosome SERTMore data for this Ligand-Target Pair