BDBM50175742 7-(8-aza-bicyclo[3.2.1]octan-3-yl)-5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)quinolin-2(1H)-one::CHEMBL199701
SMILES Fc1ccc(c(Cl)c1)-c1cc(cc2n(-c3c(Cl)cccc3Cl)c(=O)ccc12)C1CC2CCC(C1)N2
InChI Key InChIKey=PULZCVVMWDBVFZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50175742
Affinity DataIC50: 0.450nMAssay Description:Inhibition of P38 alpha MAPKMore data for this Ligand-Target Pair
Affinity DataIC50: 14.5nMAssay Description:Inhibition of LPS stimulated TNF alpha release in whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Inhibition of TNF alpha release in THP1 cellsMore data for this Ligand-Target Pair