BDBM50176372 CHEMBL201283::N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N-methyl-2-(2-(methylsulfonamidomethyl)phenylamino)acetamide

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)CNc1ccccc1CNS(C)(=O)=O

InChI Key InChIKey=CZRUZDAXOWSVEH-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176372   

TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50176372(N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataEC50:  0.520nMAssay Description:Agonist activity at kappa opioid receptor in a [35S]GTP-gamma-S functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50176372(N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50176372(N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed