BDBM50176548 5-(bicyclo[2.2.1]heptan-2-ylamino)-3-(difluoromethyl)-1-(5-(methylsulfonyl)pyridin-2-yl)-1H-pyrazole-4-carbonitrile::CHEMBL199681

SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(C(F)F)c(C#N)c1NC1CC2CCC1C2

InChI Key InChIKey=BITIDZWJAWDFKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176548   

TargetProstaglandin G/H synthase 2(Dog)
Veterinary Medicine Research and Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176548(5-(bicyclo[2.2.1]heptan-2-ylamino)-3-(difluorometh...)
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Dog)
Veterinary Medicine Research and Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176548(5-(bicyclo[2.2.1]heptan-2-ylamino)-3-(difluorometh...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed