BDBM50177058 9-Azetidin-1-yl-3-(4-ethyl-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::9-N-azetidinyl-3-(4'-ethylphenyl)-3H-5-thia-1,3,6-triazafluoren-4-one::CHEMBL225126

SMILES CCc1ccc(cc1)-n1cnc2c(sc3nccc(N4CCC4)c23)c1=O

InChI Key InChIKey=FDIVPHCBJYDOLP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177058   

TargetMetabotropic glutamate receptor 1(Rat)
Biocampus

Curated by ChEMBL
LigandPNGBDBM50177058(9-N-azetidinyl-3-(4'-ethylphenyl)-3H-5-thia-1,3,6-...)
Affinity DataIC50: 113nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177058(9-N-azetidinyl-3-(4'-ethylphenyl)-3H-5-thia-1,3,6-...)
Affinity DataIC50: 113nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177058(9-N-azetidinyl-3-(4'-ethylphenyl)-3H-5-thia-1,3,6-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed