BDBM50177086 3-(4-Ethyl-phenyl)-9-methylamino-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::9-(methylamino)-3-(4'-ethylphenyl)-3H-5-thia-1,3,6-triazafluoren-4-one::CHEMBL374815

SMILES CCc1ccc(cc1)-n1cnc2c(sc3nccc(NC)c23)c1=O

InChI Key InChIKey=VQAOBNKKATVAHJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177086   

TargetMetabotropic glutamate receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177086(3-(4-Ethyl-phenyl)-9-methylamino-3H-pyrido[3',2':4...)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Biocampus

Curated by ChEMBL
LigandPNGBDBM50177086(3-(4-Ethyl-phenyl)-9-methylamino-3H-pyrido[3',2':4...)
Affinity DataIC50: 98nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177086(3-(4-Ethyl-phenyl)-9-methylamino-3H-pyrido[3',2':4...)
Affinity DataIC50: 5.96E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed