BDBM50177125 6-(2-Chloro-4-fluoro-phenylsulfamoyl)-cyclohex-1-enecarboxylic acid ethyl ester::CHEMBL426184::ethyl 6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate

SMILES CCOC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(F)cc1Cl

InChI Key InChIKey=LEEIJTHMHDMWLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177125   

TargetToll-like receptor 4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50177125BDBM50177125(ethyl 6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cycl...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human TLR4-mediated cytokine production in mouse macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed