BDBM50177591 CHEMBL203513::[2-chloro-4-(1-methyl-1H-pyrazol-3-yl)-phenyl]-(5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6-yl)-methanone

SMILES Cn1ccc(n1)-c1ccc(C(=O)N2Cc3cccnc3Nc3ccccc23)c(Cl)c1

InChI Key InChIKey=LLXMTMODFSWNAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177591   

TargetVasopressin V2 receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177591([2-chloro-4-(1-methyl-1H-pyrazol-3-yl)-phenyl]-(5,...)
Affinity DataIC50: 183nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177591([2-chloro-4-(1-methyl-1H-pyrazol-3-yl)-phenyl]-(5,...)
Affinity DataIC50: 1.78E+3nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed