BDBM50177631 3-((3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)-1,2,4-oxadiazol-5-yl)methyl)pent-4-ynoic acid::CHEMBL204259

SMILES OC(=O)CC(Cc1nc(CCCc2ccc3CCCNc3n2)no1)C#C

InChI Key InChIKey=KZYLTZUXEHTOHA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50177631   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177631(3-((3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177631(3-((3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Integrin alphav-beta5 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177631(3-((3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177631(3-((3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of Integrin alpha-2b-beta-3 receptor by SPRA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177631(3-((3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl...)
Affinity DataIC50: 6.24E+3nMAssay Description:Inhibition of Integrin alphav-beta6 receptor expressed in HT29 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed