BDBM50177694 3-(1-butyl-trans-4,5-dimethyl-2-alpha-propylpiperidin-4-yl)phenol::CHEMBL202150

SMILES CCCCN1C[C@H](C)[C@@](C)(C[C@H]1CCC)c1cccc(O)c1

InChI Key InChIKey=VIPXJADEILSYRZ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177694   

TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177694(3-(1-butyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataIC50: 290nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177694(3-(1-butyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataKi:  550nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177694(3-(1-butyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177694(3-(1-butyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed