BDBM50177771 4'-(4-tert-Butylamino-piperidin-1-yl)-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide::CHEMBL199163

SMILES CC(C)(C)NC1CCN(CC1)c1ccc(cc1)-c1ccc(cc1)C(=O)NC1(CCCCC1)C(=O)NCC#N

InChI Key InChIKey=QYEUDSXPORTFRD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177771   

TargetProcathepsin L(Human)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50177771(4'-(4-tert-Butylamino-piperidin-1-yl)-biphenyl-4-c...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory constant against human cathepsin L using Z-Phe-Arg-AMC substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50177771(4'-(4-tert-Butylamino-piperidin-1-yl)-biphenyl-4-c...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibitory constant against human cathepsin S using Z-Val-Val-Arg-AMC substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50177771(4'-(4-tert-Butylamino-piperidin-1-yl)-biphenyl-4-c...)
Affinity DataKi:  7.60E+4nMAssay Description:Inhibitory constant against human cathepsin B using Boc-Leu-Lys-Arg-AMC substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed