BDBM50178424 (2S)-2-((2-(4,5-dichloro-6-methoxy-1,3-dioxo-2-phenyl-2,3-dihydro-1H-inden-2-yl)ethyl)(methyl)amino)-3-hydroxypropanoic acid::CHEMBL204397

SMILES COc1cc2C(=O)C(CCN(C)[C@@H](CO)C(O)=O)(C(=O)c2c(Cl)c1Cl)c1ccccc1

InChI Key InChIKey=PYGWLXDQXXPREL-XLEXHMCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178424   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178424((2S)-2-((2-(4,5-dichloro-6-methoxy-1,3-dioxo-2-phe...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of uptake of [14C]glycine into human JAR cells expressing human GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed