BDBM50178491 5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydro-dinaphtho[1,2-b;2',3'-d]furan-6-carboxylic acid methyl ester::CHEMBL383030

SMILES COC(=O)c1c(OCCCN(C)C)c2ccccc2c2oc3c(C(=O)c4ccccc4C3=O)c12

InChI Key InChIKey=QROZNTBKLCEHDK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178491   

TargetPlatelet-derived growth factor receptor beta(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178491(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178491(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibitory activity against EGFR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178491(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibitory activity against VEGFR2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178491(5-(3-dimethylamino-propoxy)-7,12-dioxo-7,12-dihydr...)
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibitory activity against FGFR1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed