BDBM50178494 5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-dinaphtho[1,2-b;2',3'-d]furan-6-carboxylic acid methyl ester::CHEMBL202162

SMILES CCN(CC)CCOc1c(C(=O)OC)c2c3c(oc2c2ccccc12)C(=O)c1ccccc1C3=O

InChI Key InChIKey=OHYFDYUPUPHUDP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178494   

TargetEpidermal growth factor receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178494(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against EGFR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178494(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibitory activity against FGFR1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178494(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibitory activity against VEGFR2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50178494(5-(2-diethylamino-ethoxy)-7,12-dioxo-7,12-dihydro-...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed