BDBM50178525 CHEMBL203731::N-(4-tert-butylphenyl)-5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-amine

SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(C)(C)C)o1

InChI Key InChIKey=DXPJRFUAXOWMTL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178525   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178525(N-(4-tert-butylphenyl)-5-(1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 380nMAssay Description:Inhibition of VEGFR2 by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178525(N-(4-tert-butylphenyl)-5-(1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 890nMAssay Description:Inhibition of VEGFR1 by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178525(N-(4-tert-butylphenyl)-5-(1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed