BDBM50178775 (S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide::(S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxylic acid amide::CHEMBL198609

SMILES c1cc2c(cc1Cl)c3c([nH]2)[C@H](CCCC3)C(=O)N

InChI Key InChIKey=ABIVOOWWGYJNLV-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178775   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Elixir Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178775((S)-2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]in...)
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)