BDBM50178923 7-(3-amino-4-fluorophenyl)-9-cyclopropyl-6-fluoroisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione::CHEMBL205729

SMILES Nc1cc(ccc1F)-c1cc2n(C3CC3)c3s[nH]c(=O)c3c(=O)c2cc1F

InChI Key InChIKey=HFRGSVIKEOBJHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178923   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178923(7-(3-amino-4-fluorophenyl)-9-cyclopropyl-6-fluoroi...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178923(7-(3-amino-4-fluorophenyl)-9-cyclopropyl-6-fluoroi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed