BDBM50180386 3-(2-chloropyrimidin-4-yl)-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine::CHEMBL204390

SMILES FC(F)(F)c1ccn2c(cnc2n1)-c1ccnc(Cl)n1

InChI Key InChIKey=KVTRKSLNWMZSSN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180386   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180386(3-(2-chloropyrimidin-4-yl)-7-(trifluoromethyl)imid...)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180386(3-(2-chloropyrimidin-4-yl)-7-(trifluoromethyl)imid...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed